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mciZ [2017-10-26 14:20:12]
function
inhibits GTPase activity of FtsZ and Z ring formation during sporulation
product
FtsZ inhibition peptide
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]Gene
Coordinates
2,459,114 → 2,459,288
Protein
Catalyzed reaction/ biological activity
inhibits GTPase activity of [protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ]and Z ring formation during [SW|sporulation]Structure
[PDB|2MRW] [Pubmed|25848052][PDB|4U39] (the [protein|search|F150B9B75C8352950B9BB71E29CB156B66AA6CDD]-[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] complex) [Pubmed|25848052][SW|Interactions]
[protein|search|F150B9B75C8352950B9BB71E29CB156B66AA6CDD]-[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] [Pubmed|18284588], KD 150 nM [Pubmed|25848052]References
Reviews
Original publications
18284588,25848052,23237472,27752253